Infertility prevalence and the methods of estimation from 1990 to 2021: a systematic review and meta-analysis

Study question: What is the contemporary prevalence of infertility in world populations and how do they differ by methodological and study characteristics?

Summary answer: Pooled estimates of lifetime and period prevalence of 12-month infertility were 17.5% and 12.6%, respectively, but this varied by study population and methodological approach.

Study design size duration: We conducted a systematic review and meta-analysis. Six electronic databases, websites of relevant organizations, and conference proceedings were systematically searched. Searches were limited to those published between 1 January 1990 and 11 March 2021, with no language restrictions.

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Published in Human Reproduction Open.